Psychedelic Culture 2024 is a two-day in-person conference that promises to be a meaningful gathering of minds and spirits—hosted at the Brava Theater, a cooperative led by women in the traditional Latin neighborhood of San Francisco, California.

That substance is 5-MEO-DMT (5-methoxy-N,N-dimethyltryptamine) - a psychedelic naturally occurring in a number of plants (including the fabled ayahuasca) and in one very special species of toad: The Sonoran Desert Toad (native to the US state of Arizona and the Mexican state of Sonora), also sometimes referred to as the Colorado River Toad.

Toloache is known as an herbal love brew in Mexico, but it has other benefits, too - and some serious side effects.